The Journal of Urology

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Advancing the specialty–business, policy and practice 
Urology Practice, an official journal of the American Urological Association, focuses on clinical trends, challenges and practice applications in the four areas of Business, Health Policy, the Specialty and Patient Care.

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Featured Articles


 
 

A Pilot Study to Evaluate the Role of Magnetic Resonance Imaging for Prostate Cancer Screening in the General Population
Robert K. Nam, Christopher J.D. Wallis, Jessica Stojcic-Bendavid, Laurent Milot, Christopher Sherman, Linda Sugar, Masoom A. Haider

 
 

Characteristics of Anteriorly Located Prostate Cancer and the Usefulness of Multiparametric Magnetic Resonance Imaging for Diagnosis
Myong Kim, Seung-Kwon Choi, Myungchan Park, Myungsun Shim, Cheryn Song, In Gab Jeong, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn

 
 

Positive Surgical Margins Increase Risk of Recurrence after Partial Nephrectomy for High Risk Renal Tumors
Paras H. Shah, Daniel M. Moreira, Zhamshid Okhunov, Vinay R. Patel, Sameer Chopra, Aria A. Razmaria, Manaf Alom, Arvin K. George, Oksana Yaskiv, Michael J. Schwartz, Mihir Desai, Manish A. Vira, Lee Richstone, Jaime Landman, Arieh L. Shalhav, Inderbir Gill, Louis R. Kavoussi

 
 

This Month In ...


 
 

This Month in Adult Urology 
Joseph A. Smith 

 
 

This Month in Pediatric Urology 
Mark P. Cain 

 
 

This Month in Investigative Urology 
Karl-Erik Andersson 

 
 

Editorials


 
 

Treatment of Patients with Positive Margins after Partial Nephrectomy 
Simon P. Kim, Robert Abouassaly 

 
 

Gleason Score 7: When Qualitative Change Becomes Quantitative Change 
T. Van der Kwast 

 
 

The Ethics of Gender in Pediatric Reconstructive Urology 
David A. Diamond 

 
 

Opposing Views


 
 

Surgery Provides Better Oncologic Outcomes than Radiation for the Treatment of Prostate Cancer 
Mack Roach 

 
 

Surgery Provides Better Oncologic Outcomes than Radiation for the Treatment of Prostate Cancer 
Laurence Klotz, Christopher P. Evans 

 
 

Review Article


 
 

Current Status of Simulation and Training Models in Urological Surgery: A Systematic Review 
Abdullatif Aydin, Ahmed M.A. Shafi, Muhammad Shamim Khan, Prokar Dasgupta, Kamran Ahmed 

 
 

Editorial Comment 
Chandru P. Sundaram 

 
 

Editorial Comment 
Elspeth M. McDougall 

 
 

Adult Urology


 
 

Oncology: Adrenal/Renal/Upper Tract/Bladder


 
 

The Usefulness of Chest X-Rays for T1a Renal Cell Carcinoma Surveillance 
Noah E. Canvasser, Kylee Stouder, Aaron H. Lay, Jeffrey C. Gahan, Yair Lotan, Vitaly Margulis, Ganesh V. Raj, Arthur I. Sagalowsky, Jeffrey A. Cadeddu 

 
 

Positive Surgical Margins Increase Risk of Recurrence after Partial Nephrectomy for High Risk Renal Tumors 
Paras H. Shah, Daniel M. Moreira, Zhamshid Okhunov, Vinay R. Patel, Sameer Chopra, Aria A. Razmaria, Manaf Alom, Arvin K. George, Oksana Yaskiv, Michael J. Schwartz, Mihir Desai, Manish A. Vira, Lee Richstone, Jaime Landman, Arieh L. Shalhav, Inderbir Gill, Louis R. Kavoussi 

 
 

Editorial Comment 
Mark W. Ball, Mohamad E. Allaf 

 
 

Editorial Comment 
Mary McHugh, Marc C. Smaldone 

 
 

Reply by Authors 
 

 
 

The Presence of Vascular Mimicry Predicts High Risk of Clear Cell Renal Cell Carcinoma after Radical Nephrectomy 
Lin Zhou, Yuan Chang, Le Xu, Zheng Liu, Qiang Fu, Yuanfeng Yang, Zongming Lin, Jiejie Xu 

 
 

Editorial Comment 
Sumi Dey, Brian R. Lane 

 
 

Association of Itraconazole, a Hedgehog Inhibitor, and Bladder Cancer 
Ronac Mamtani, Yu-Xiao Yang, Frank I. Scott, James D. Lewis, Ben Boursi 

 
 

Urological Survey


 
 

Urological Oncology: Adrenal, Renal, Ureteral and Retroperitoneal Tumors


 
 

Re: Guideline of Guidelines: Follow-up after Nephrectomy for Renal Cell Carcinoma 
M. Pilar Laguna 

 
 

Re: Prediction of Pulmonary Metastasis in Renal Cell Carcinoma Patients with Indeterminate Pulmonary Nodules 
M. Pilar Laguna 

 
 

Laparoscopy/New Technology


 
 

Re: Urinary Fistula after Robot-Assisted Partial Nephrectomy: A Multicentre Analysis of 1,791 Patients 
Jeffrey A. Cadeddu 

 
 

Re: Computed Tomography Contrast Enhancement following Renal Cryoablation—Does it Represent Treatment Failure? 
Jeffrey A. Cadeddu 

 
 

Urological Oncology: Bladder, Penis and Urethral Cancer, and Basic Principles of Oncology


 
 

Re: Whole-Exome Sequencing of Muscle-Invasive Bladder Cancer Identifies Recurrent Mutations of UNC5C and Prognostic Importance of DNA Repair Gene Mutations on Survival 
Sam S. Chang 

 
 

Re: The Association of ABO Blood Type with Disease Recurrence and Mortality among Patients with Urothelial Carcinoma of the Bladder Undergoing Radical Cystectomy 
Sam S. Chang 

 
 

Socioeconomic Factors, Urological Epidemiology and Practice Patterns


 
 

Re: Effectiveness of Adjuvant Chemotherapy for Locally Advanced Bladder Cancer 
David F. Penson 

 
 

Re: The Correlation of Media Ranking’s “Best” Hospitals and Surgical Outcomes following Radical Cystectomy for Urothelial Cancer 
David F. Penson 

 
 

Oncology: Prostate/Testis/Penis/Urethra


 
 

Serial Percent Free Prostate Specific Antigen in Combination with Prostate Specific Antigen for Population Based Early Detection of Prostate Cancer 
Donna Pauler Ankerst, Jonathan Gelfond, Martin Goros, Jesus Herrera, Andreas Strobl, Ian M. Thompson, Javier Hernandez, Robin J. Leach 

 
 

A Pilot Study to Evaluate the Role of Magnetic Resonance Imaging for Prostate Cancer Screening in the General Population 
Robert K. Nam, Christopher J.D. Wallis, Jessica Stojcic-Bendavid, Laurent Milot, Christopher Sherman, Linda Sugar, Masoom A. Haider 

 
 

Editorial Comment 
Xiaosong Meng, Samir S. Taneja 

 
 

Editorial Comment 
Pedro Recabal 

 
 

Editorial Comment 
Annerleim Walton-Diaz 

 
 

Reply by Authors 
 

 
 

Characteristics of Anteriorly Located Prostate Cancer and the Usefulness of Multiparametric Magnetic Resonance Imaging for Diagnosis 
Myong Kim, Seung-Kwon Choi, Myungchan Park, Myungsun Shim, Cheryn Song, In Gab Jeong, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn 

 
 

The Efficacy of Multiparametric Magnetic Resonance Imaging and Magnetic Resonance Imaging Targeted Biopsy in Risk Classification for Patients with Prostate Cancer on Active Surveillance 
Pedro Recabal, Melissa Assel, Daniel D. Sjoberg, Daniel Lee, Vincent P. Laudone, Karim Touijer, James A. Eastham, Hebert A. Vargas, Jonathan Coleman, Behfar Ehdaie 

 
 

Editorial Comment 
Joshua A. Halpern, Jonathan E. Shoag, Jim C. Hu 

 
 

Editorial Comment 
Baris Turkbey, Arvin K. George, Peter L. Choyke, Peter A. Pinto 

 
 

Systemic Radioligand Therapy with 177Lu Labeled Prostate Specific Membrane Antigen Ligand for Imaging and Therapy in Patients with Metastatic Castration Resistant Prostate Cancer 
Matthias M. Heck, Margitta Retz, Calogero D'Alessandria, Isabel Rauscher, Klemens Scheidhauer, Tobias Maurer, Enno Storz, Friederike Janssen, Margret Schottelius, Hans-Jürgen Wester, Jürgen E. Gschwend, Markus Schwaiger, Robert Tauber, Matthias Eiber 

 
 

Editorial Comment 
Andrei Iagaru 

 
 

Editorial Comment 
Rafael Sanchez-Salas 

 
 

Prospective Quality of Life in Men Choosing Active Surveillance Compared to Those Biopsied but not Diagnosed with Prostate Cancer 
Khanh N. Pham, Jennifer Cullen, Lauren M. Hurwitz, Erika M. Wolff, Katherine E. Levie, Katherine Odem-Davis, John S. Banerji, Inger L. Rosner, Timothy C. Brand, James O. L’Esperance, Joseph R. Sterbis, Christopher R. Porter 

 
 

Editorial Comment 
Nachiketh Soodana Prakash, Bruno Nahar, Sanoj Punenn 

 
 

Notable Outcomes and Trackable Events after Surgery: Evaluating an Uncomplicated Recovery after Radical Prostatectomy 
Stacie N. Myers, Khurshid R. Ghani, Rodney L. Dunn, Brian R. Lane, Edward W. Schervish, Yuqing Gao, Susan M. Linsell, David C. Miller, James E. Montie, James M. Dupree 

 
 

Prognostic Value of Percent Gleason Grade 4 at Prostate Biopsy in Predicting Prostatectomy Pathology and Recurrence 
Adam I. Cole, Todd M. Morgan, Daniel E. Spratt, Ganesh S. Palapattu, Chang He, Scott A. Tomlins, Alon Z. Weizer, Felix Y. Feng, Angela Wu, Javed Siddiqui, Arul M. Chinnaiyan, Jeffrey S. Montgomery, Lakshmi P. Kunju, David C. Miller, Brent K. Hollenbeck, John T. Wei, Rohit Mehra 

 
 

Urological Survey


 
 

Urological Oncology: Prostate Cancer


 
 

Re: Adverse Health Events following Intermittent and Continuous Androgen Deprivation in Patients with Metastatic Prostate Cancer 
Samir S. Taneja 

 
 

Re: Risk Group and Death from Prostate Cancer: Implications for Active Surveillance in Men with Favorable Intermediate-Risk Prostate Cancer 
Samir S. Taneja 

 
 

Re: Gleason Misclassification Rate is Independent of Number of Biopsy Cores in Systematic Biopsy 
Samir S. Taneja 

 
 

Re: Focal Ablation Targeted to the Index Lesion in Multifocal Localised Prostate Cancer: A Prospective Development Study 
Samir S. Taneja 

 
 

Imaging


 
 

Re: Molecular Imaging of Prostate Cancer 
Cary Siegel 

 
 

Urological Oncology: Testis Cancer and Advances in Oncologic Therapy


 
 

Re: Cardiovascular Disease Mortality after Chemotherapy or Surgery for Testicular Nonseminoma: A Population-Based Study 
Jerome P. Richie 

 
 

Infection/Inflammation


 
 

Fibrinogen Release and Deposition on Urinary Catheters Placed during Urological Procedures 
Ana L. Flores-Mireles, Jennifer N. Walker, Tyler M. Bauman, Aaron M. Potretzke, Henry L. Schreiber, Alyssa M. Park, Jerome S. Pinkner, Michael G. Caparon, Scott J. Hultgren, Alana Desai 

 
 

Recurrent Urinary Tract Infections Due to Bacterial Persistence or Reinfection in Women—Does This Factor Impact Upper Tract Imaging Findings? 
Yuefeng (Rose) Wu, Lauren L. Rego, Alana L. Christie, Rebecca S. Lavelle, Feras Alhalabi, Philippe E. Zimmern 

 
 

Editorial Comment 
Anthony J. Schaeffer 

 
 

Reply by Authors 
 

 
 

Autonomic Testing in Women with Chronic Pelvic Pain 
Gisela Chelimsky, Pippa Simpson, Noel McCabe, Liyun Zhang, Thomas Chelimsky collaborative 

 
 

Analysis of Gut Microbiome Reveals Significant Differences between Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Controls 
Daniel A. Shoskes, Hannah Wang, Alan S. Polackwich, Barbara Tucky, Jessica Altemus, Charis Eng 

 
 

Editorial Comment 
J. Curtis Nickel 

 
 

Urological Survey


 
 

Infection and Inflammation of Genitourinary Tract


 
 

Re: Urinary Tract Infections in Older Men 
Edward M. Schaeffer 

 
 

Re: Uropathogenic Escherichia coli Induces Chronic Pelvic Pain 
Edward M. Schaeffer 

 
 

Re: Infections after Fiducial Marker Implantation for Prostate Radiotherapy: Are we Underestimating the Risks? 
Edward M. Schaeffer 

 
 

Urolithiasis/Endourology


 
 

Anticipating the Unintended Consequences of Closing the Door on Physician Self-Referral 
Matthew J. Resnick, Amy J. Graves, W. Stuart Reynolds, Daniel A. Barocas, R. Lawrence Van Horn, Melinda B. Buntin, David F. Penson 

 
 

Editorial Comment 
Hung-Jui Tan, Mark S. Litwin 

 
 

Editorial Comment 
Angela B. Smith 

 
 

Urological Survey


 
 

Urolithiasis/Endourology


 
 

Re: Ways of Calcium Reabsorption in the Kidney 
Dean G. Assimos 

 
 

Re: Do Urologists Follow the Golden Rule? A Global Urolithiasis Management Study by the Clinical Research Office of the Endourological Society 
Dean G. Assimos 

 
 

Trauma/Reconstruction/Diversion


 
 

Measuring and Predicting Patient Dissatisfaction after Anterior Urethroplasty Using Patient Reported Outcomes Measures 
Laura A. Bertrand, Bryan B. Voelzke, Sean P. Elliott, Jeremy B. Myers, Benjamin N. Breyer, Alex J. Vanni, Christopher D. McClung, Christopher A. Tam, Gareth J. Warren, Bradley A. Erickson 

 
 

Editorial Comment 
Richard A. Santucci 

 
 

Reply by Authors 
 

 
 

Urological Survey


 
 

Trauma, and Genital and Urethral Reconstruction


 
 

Re: Two-Sided Urethra-Sparing Reconstruction Combining Dorsal Preputial Skin plus Ventral Buccal Mucosa Grafts for Tight Bulbar Strictures 
Allen F. Morey 

 
 

Re: The Vascular and Neurogenic Factors Associated with Erectile Dysfunction in Patients after Pelvic Fractures 
Allen F. Morey 

 
 

Re: Substitution Urethroplasty or Anastomotic Urethroplasty for Bulbar Urethra Strictures? Or Endoscopic Urethrotomy? Opinion: Substitution Urethroplasty 
Allen F. Morey 

 
 

Diagnostic Urology, Urinary Diversion and Perioperative Care


 
 

Re: The Impact of Transtomal Rigid Endoscopy in Continent Cutaneous Urinary Diversions 
David S. Wang 

 
 

Re: Surgical Checklist Implementation Project: The Impact of Variable WHO Checklist Compliance on Risk-Adjusted Clinical Outcomes after National Implementation: A Longitudinal Study 
David S. Wang 

 
 

Re: Postoperative Care Using a Secure Online Patient Portal: Changing the (Inter)Face of General Surgery 
David S. Wang 

 
 

Geriatrics


 
 

Re: Do Surgical Trainees Believe They are Adequately Trained to Manage the Ageing Population? A UK Survey of Knowledge and Beliefs in Surgical Trainees 
Tomas L. Griebling 

 
 

Re: The Relationship between Urinary Total Polyphenols and the Frailty Phenotype in a Community-Dwelling Older Population: The InCHIANTI Study 
Tomas L. Griebling 

 
 

Re: Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery 
Tomas L. Griebling 

 
 

Voiding Dysfunction


 
 

Systemic Nonurological Symptoms in Patients with Overactive Bladder 
H. Henry Lai, Joel Vetter, Sanjay Jain, Gerald L. Andriole 

 
 

Somatic Comorbidity in Women with Overactive Bladder Syndrome 
Daniel Altman, Anastasia N. Iliadou, Cecilia Lundholm, Ian Milsom, Nancy L. Pedersen 

 
 

Editorial Comment 
John W. Warren 

 
 

Urgency Incontinence before and after Revision of a Synthetic Mid Urethral Sling 
Iryna M. Crescenze, Nitya Abraham, Jianbo Li, Howard B. Goldman, Sandip Vasavada 

 
 

Outcomes of Autologous Fascia Pubovaginal Sling for Patients with Transvaginal Mesh Related Complications Requiring Mesh Removal 
Olugbemisola McCoy, Taylor Vaughan, S. Walker Nickles, Matt Ashley, Lara S. MacLachlan, David Ginsberg, Eric Rovner 

 
 

Noninvasive Diagnosis of Bladder Outlet Obstruction in Patients with Lower Urinary Tract Symptoms Using Ultrasound Decorrelation Analysis 
Muhammad Arif, Jan Groen, Egbert R. Boevé, Chris L. de Korte, Tim Idzenga, Ron van Mastrigt 

 
 

Editorial Comment 
Ahmed El-Zawahry 

 
 

Urological Survey


 
 

Voiding Function and Dysfunction, Bladder Physiology and Pharmacology, and Female Urology


 
 

Re: Comparison of Short Term Outcomes of Sacral Nerve Stimulation and Intradetrusor Injection of OnabotulinumtoxinA (Botox) in Women with Refractory Overactive Bladder 
Alan J. Wein 

 
 

Re: Cost-Effectiveness of an Internet-Based Treatment Program for Stress Urinary Incontinence 
Alan J. Wein 

 
 

Re: Does Defective Volume Sensation Contribute to Detrusor Underactivity? 
Alan J. Wein 

 
 

Re: Guideline of Guidelines: Urinary Incontinence 
Alan J. Wein 

 
 

Re: External Urethral Sphincter Electromyography in Asymptomatic Women and the Influence of the Menstrual Cycle 
Alan J. Wein 

 
 

Re: A Review of Detrusor Overactivity and the Overactive Bladder after Radical Prostate Cancer Treatment 
Alan J. Wein 

 
 

Benign Prostatic Hyperplasia


 
 

Re: Effect of Weight Reduction on the Severity of Lower Urinary Tract Symptoms in Obese Male Patients with Benign Prostatic Hyperplasia: A Randomized Controlled Trial 
Steven A. Kaplan 

 
 

Re: Long-Term Safety and Efficacy of Single-Tablet Combinations of Solifenacin and Tamsulosin Oral Controlled Absorption System in Men with Storage and Voiding Lower Urinary Tract Symptoms: Results from the NEPTUNE Study and NEPTUNE II Open-Label Extension 
Steven A. Kaplan 

 
 

Re: Comparison of Tamsulosin plus Serenoa repens with Tamsulosin in the Treatment of Benign Prostatic Hyperplasia in Korean Men: 1-Year Randomized Open Label Study 
Steven A. Kaplan 

 
 

Transplantation/Vascular Surgery


 
 

Urological Survey


 
 

Renal Transplantation and Renovascular Hypertension


 
 

Re: Estimated GFR for Living Kidney Donor Evaluation 
David A. Goldfarb 

 
 

Re: Kidney Retransplantation in the Ipsilateral Iliac Fossa: A Surgical Challenge 
David A. Goldfarb 

 
 

Re: Trends and Outcomes in Right vs. Left Living Donor Nephrectomy: An Analysis of the OPTN/UNOS Database of Donor and Recipient Outcomes—Should We be Doing More Right-Sided Nephrectomies? 
David A. Goldfarb 

 
 

Laparoscopy/New Technology


 
 

Re: Robot-Assisted Laparoscopic Donor Nephrectomy vs Standard Laparoscopic Donor Nephrectomy: A Prospective Randomized Comparative Study 
Jeffrey A. Cadeddu 

 
 

Sexual Function/Infertility


 
 

Erectile Function Recovery after Radical Prostatectomy in Men with High Risk Features 
Pedro Recabal, Melissa Assel, John E. Musser, Ronald J. Caras, Daniel D. Sjoberg, Jonathan A. Coleman, John P. Mulhall, Raul O. Parra, Peter T. Scardino, Karim Touijer, James A. Eastham, Vincent P. Laudone 

 
 

Editorial Comment 
Bertram Yuh 

 
 

Urological Survey


 
 

Male and Female Sexual Function and Dysfunction; Andrology


 
 

Re: A Prospective, Randomized, Placebo-Controlled Trial of On-Demand vs. Nightly Sildenafil Citrate as Assessed by RigiScan and the International Index of Erectile Function 
Allen D. Seftel 

 
 

Re: Simultaneous Detection of Three Phosphodiesterase Type 5 Inhibitors and Eight of Their Analogs in Lifestyle Products and Screening for Adulterants by High-Performance Thin-Layer Chromatography 
Allen D. Seftel 

 
 

Re: Tadalafil 5 mg Once Daily for the Treatment of Erectile Dysfunction during a 6-Month Observational Study (EDATE): Impact of Patient Characteristics and Comorbidities 
Allen D. Seftel 

 
 

Re: Effects of Testosterone Treatment in Older Men 
Allen D. Seftel 

 
 

Re: Effects of Testosterone Replacement Therapy on Lower Urinary Tract Symptoms: A Systematic Review and Meta-Analysis 
Allen D. Seftel 

 
 

Re: Effect of Lifestyle Intervention on the Hormonal Profile of Frail, Obese Older Men 
Allen D. Seftel 

 
 

Re: A Pilot Study Using a Web Survey to Identify Characteristics that Influence Hypogonadal Men to Initiate Testosterone Replacement Therapy 
Allen D. Seftel 

 
 

Re: Six Months of Daily Treatment with Vardenafil Improves Parameters of Endothelial Inflammation and of Hypogonadism in Male Patients with Type 2 Diabetes and Erectile Dysfunction: A Randomized, Double-Blind, Prospective Trial 
Allen D. Seftel 

 
 

Geriatrics


 
 

Re: Association between Testosterone Supplementation Therapy and Thrombotic Events in Elderly Men 
Tomas L. Griebling 

 
 

Re: Examining Associations between Sexual Behaviours and Quality of Life in Older Adults 
Tomas L. Griebling 

 
 

Male Infertility


 
 

Re: Use of Suboptimal Sperm Increases the Risk of Aneuploidy of the Sex Chromosomes in Preimplantation Blastocyst Embryos 
Craig Niederberger 

 
 

Re: DNA Fragmentation in Brighter Sperm Predicts Male Fertility Independently from Age and Semen Parameters 
Craig Niederberger 

 
 

Re: Molecular Karyotyping of Single Sperm with Nuclear Vacuoles Identifies More Chromosomal Abnormalities in Patients with Testiculopathy than Fertile Controls: Implications for ICSI 
Craig Niederberger 

 
 

Re: Cryopreservation of Testicular Tissue before Long-Term Testicular Cell Culture Does Not Alter In Vitro Cell Dynamics 
Craig Niederberger 

 
 

Re: Sperm Freezing to Address the Risk of Azoospermia on the Day of ICSI 
Craig Niederberger 

 
 

Re: Subfertility Increases Risk of Testicular Cancer: Evidence from Population-Based Semen Samples 
Craig Niederberger 

 
 

Re: Spermatogenesis in Hodgkin’s Lymphoma Patients: A Retrospective Study of Semen Quality before and after Different Chemotherapy Regimens 
Craig Niederberger 

 
 

Re: Effect of Male Body Mass Index on Live-Birth Sex Ratio of Singletons after Assisted Reproduction Technology 
Craig Niederberger 

 
 

Re: Mediterranean and Western Dietary Patterns are Related to Markers of Testicular Function among Healthy Men 
Craig Niederberger 

 
 

Re: Psychological Stress and Testicular Function: A Cross-Sectional Study of 1,215 Danish Men 
Craig Niederberger 

 
 

Pediatric Urology


 
 

24-Hour Urinary Parameters in Overweight and Obese Children with Urolithiasis 
Jathin Bandari, Pankaj P. Dangle, Timothy D. Lyon, Andy Lee, Francis X. Schneck, Glenn M. Cannon, Heidi A. Stephany, Michael C. Ost 

 
 

Gender Identity and Sex Role of Patients Operated on for Bladder Exstrophy-Epispadias 
Seppo Taskinen, Janne S. Suominen, Aino K. Mattila 

 
 

Vancouver Symptom Score for Dysfunctional Elimination Syndrome: Reliability and Validity of the Dutch Version 
Lisette A. ’t Hoen, Ida J. Korfage, Jacintha T.C.M. Verhallen, Marjan J. van Ledden-Klok, Joop van den Hoek, Bertil F.M. Blok, Jeroen R. Scheepe 

 
 

Long-Term Outcome of Low Scrotal Approach Orchiopexy without Ligation of the Processus Vaginalis 
Taiju Hyuga, Shina Kawai, Shigeru Nakamura, Taro Kubo, Hideo Nakai 

 
 

Editorial Comment 
Andrew J. Kirsch 

 
 

Urological Survey


 
 

Pediatric Urology


 
 

Re: The “Flowerpot” Sign: Inference of Poor Renal Function in High Grade Vesicoureteral Reflux by Calyceal Orientation 
Douglas A. Canning 

 
 

Re: Renal Function in Survivors of Nonsyndromic Wilms Tumor Treated with Unilateral Radical Nephrectomy 
Douglas A. Canning 

 
 

Re: Overall Survival and Renal Function of Patients with Synchronous Bilateral Wilms Tumor Undergoing Surgery at a Single Institution 
Douglas A. Canning 

 
 

Re: Failed Hypospadias Repair: An Algorithm for Secondary Reconstruction Using Remaining Local Tissue 
Douglas A. Canning 

 
 

Urolithiasis/Endourology


 
 

Re: Prevalence of Monogenic Causes in Pediatric Patients with Nephrolithiasis or Nephrocalcinosis 
Dean G. Assimos 

 
 

Re: Renal Tubular Dysfunction in Pediatric Urolithiasis: Proteomic Evidence 
Dean G. Assimos 

 
 

New Technology and Techniques


 
 

Histopathological Outcomes after Irreversible Electroporation for Prostate Cancer: Results of an Ablate and Resect Study 
W. van den Bos, R.R. Jurhill, D.M. de Bruin, C.D. Savci-Heijink, A.W. Postema, P.G.K. Wagstaff, B.G. Muller, I.M. Varkarakis, A. Skolarikos, P.J. Zondervan, M.P. Laguna Pes, T.M. de Reijke, J.J.M.C.H. de la Rosette 

 
 

Editorial Comment 
Hashim Ahmed, Mark Emberton 

 
 

Investigative Urology


 
 

Assessing Cancer Risk on Novel 29 MHz Micro-Ultrasound Images of the Prostate: Creation of the Micro-Ultrasound Protocol for Prostate Risk Identification 
Sangeet Ghai, Gregg Eure, Vincent Fradet, Matthew E. Hyndman, Theresa McGrath, Brian Wodlinger, Christian P. Pavlovich 

 
 

Editorial Comment 
Ferdinand Frauscher, Jean de la Rosette 

 
 

Reply by Authors 
 

 
 

Integrated Loss of miR-1/miR-101/miR-204 Discriminates Metastatic from Nonmetastatic Penile Carcinomas and Can Predict Patient Outcome 
Juliane M. Hartz, David Engelmann, Katharina Fürst, Stephan Marquardt, Alf Spitschak, Deborah Goody, Chris Protzel, Oliver W. Hakenberg, Brigitte M. Pützer 

 
 

Redefining Healthy Urine: A Cross-Sectional Exploratory Metagenomic Study of People With and Without Bladder Dysfunction 
Suzanne L. Groah, Marcos Pérez-Losada, Ljubica Caldovic, Inger H. Ljungberg, Bruce M. Sprague, Eduardo Castro-Nallar, Neel J. Chandel, Michael H. Hsieh, Hans G. Pohl 

 
 

Role of PAR2 in the Development of Lower Urinary Tract Dysfunction 
Kenny Roman, Stephen F. Murphy, Joseph D. Done, Kevin E. McKenna, Anthony J. Schaeffer, Praveen Thumbikat 

 
 

Urodynamic and Immunohistochemical Evaluation of Intravesical Botulinum Toxin A Delivery Using Low Energy Shock Waves 
Yao-Chi Chuang, Tung-Liang Huang, Pradeep Tyagi, Chao-Cheng Huang 

 
 

Promising Effects of a Novel EP2 and EP3 Receptor Dual Agonist, ONO-8055, on Neurogenic Underactive Bladder in a Rat Lumbar Canal Stenosis Model 
Noritoshi Sekido, Jun Kida, Hiroko Mashimo, Daisuke Wakamatsu, Hiroki Okada, Hidekazu Matsuya 

 
 

Urological Survey


 
 

Uro-Science


 
 

Re: Stable Inhibitory Activity of Regulatory T Cells Requires the Transcription Factor Helios 
Anthony Atala 

 
 

Re: Expression Array Analysis of the Hepatocyte Growth Factor Invasive Program 
Anthony Atala 

 
 

Re: Dietary Flavonoid Fisetin Binds to β-Tubulin and Disrupts Microtubule Dynamics in Prostate Cancer Cells 
Anthony Atala 

 
 

Urological Oncology: Bladder, Penis and Urethral Cancer, and Basic Principles of Oncology


 
 

Re: Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy 
Sam S. Chang 

 
 

Letters to the Editor/Errata


 
 

Re: Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction 
Lin Chen, Jin Yang, Hai-feng Hu, Zi-li Wang 

 
 

Reply by Authors 
 

 
 

Re: Microsurgical Spermatic Cord Denervation as a Treatment for Chronic Scrotal Content Pain: A Multicenter Open Label Trial 
S.B. Patil, Nilesh Guru, V.S. Kundargi, B.S. Patil, Nikhil Patil, Kshitiz Ranka 

 
 

Reply by Authors 
 

 
 

Re: Robotic Level III Inferior Vena Cava Tumor Thrombectomy: Initial Series 
Priyank Yadav, Saurabh Vashishtha, Anil Mandhani 

 
 

Re: Evaluation and Management of the Adolescent Varicocele 
Mark A. Faasse 

 
 

CME Enrollment/Questionnaire


 
 

The Journal of Urology® Home Study Course 2016 Volume 195/196 
 

 
 

Information for Authors


 
 

Information for Authors 
 

 
 

Frontmatter


 
 

Editorial Board